Volume 18 Part 1 Article 58: Unravel the Chemistry and Biology of a Valuable Medicinal Mushroom¿Antrodia camphorate

Volume 18 Part 1 Article 58
Year 2012
Title: Unravel the Chemistry and Biology of a Valuable Medicinal Mushroom¿Antrodia camphorate
Authors: Kelvin Sze-Yin Leung and Patrick Ying-Kit Yue

Abstract:

Antrodia camphorata (AC), also known as Antrodia cinnamomea, is an extremely rare fungus native to the forested regions of Chinese Taipei. It is also a traditional Chinese medicine, and Taiwanese aborigines being applied for treating liver diseases and protecting from food and drug intoxication. Scientific studies have demonstrated that AC crude extracts and its pure chemical compounds possess a variety of beneficial functions such as anti-hypertensive, anti-hyperlipidemic, anti-inflammatory, anti-oxidant, anti-tumor, and immuno-modulatory activities. Recent studies have shown that many of these biological and pharmacological activities can be attributed to various active chemical constituents including polysaccharides, terpenoids, steroids, lignans, benzoquinone derivatives, benzenoids, maleic and succinic acid derivatives.

In the present presentation, we will first share some chemistry and biology of AC. These include the chemical constituents and associated biological activities. Chemical fingerprint has been used to standardize the production and quality control of this valuable medicinal mushroom. We will also discuss on the pharmacokinetics features of two isolated active components, antrodin B and antrodin C, derived from AC. Lastly, we will focus on the potential anti-alcoholic effect of AC.

Please login to download the PDF for this proceeding.