Volume 12 Part 1 Article 4
Title: Fungicide Resistance in Agaricus bisporos II. In Vivo Carboxin Resistance and Disease Control
Authors: M.P. Challen, K.L. Wilson and T.J. Elliott
A breeding strategy that employs induced antimetabolite resistances should facilitate the in vitro detection and production of novel hybrid mushroccn strains (Elliott 1979). Recently, a number of mutants resistant to fungicides and other antimetabolites have been recovered using UV mutagenesis (Elliott & Challen 1985; Challen & Elliott 1987; Challen, Wilson & Elliott , this vol.). In addition to their breeding potential mutants resistant to commercial fungicides offer improved prospects for the control of fungal diseases during cropping (Elliott & Challen 1983).
Many fungicides have been shown to control fungal pathogens such as Verticillium fungicola (Preuss) Hassebr. var. fungicola, but concomitant reductions in crop yield have precluded their use (Gandy 1972; Gandy & Spencer 1976, 1978, 1981). In recent years, prochloraz has been the only conpound available for the control of this disease (Fletcher 1981). Universal use of a single fungicide however, involves a high risk of the pathogen developing resistance.
Small scale cropping trials of mutants resistant to the fungicide carboxin have been carried out at the IHR-Littlehampton with two aims:
(i) to determine if mutant strains were resistant to the fungicide in vivo (ii) to test the disease control value of mutant strains coupled with carboxin applications.