Volume 19 Part 1 Article 89
Title: High-throughput screening of microorganisms and plant extracts with antifungal activity against T.aggressivum
Author: S.J.W. Hakken, E. Lagendijk, A. Thiele, C. van der Horst, C.A.M.J.J. van den Hondel and B.C. Lokman
The commercial cultivation of mushrooms is susceptible to the growth of ‘weed’ fungi which can cause substantial loss of yields. Due to increasing resistance against the currently used antifungals combined with their often harmful nature there is a growing demand for new antifungals. In this research a reporter system to measure fungal stress, previously developed in A.niger, was implemented in the fungus Trichoderma aggressivum allowing us to screen for antifungal activity against this strain.