Volume 19 Part 1 Article 130: Influence of Grifola frondosa polysaccharide on preventive effects of avian influenza inactivated vaccine

Volume 19 Part 1 Article 130
Year 2016
Title: Influence of Grifola frondosa polysaccharide on preventive effects of avian influenza inactivated vaccine
Author: Ding Hai-cheng, Zhou Chang-yan, Liu Cheng-chu

Abstract:
Maitake (Grifola frondosa) is a kind of rare mushroom. Modern medical research showed that, as the main active ingredient, Grifola frondosa polysaccharide (GFP) showed significant anti-cancer, liver protection, immunity improvment and many other pharmacological activities. As a serious threat to the poultry industry around the world, bird flu (Avian Influenza, AI), especially the H5 and H7 subtypes, which caused highly pathogenic avian influenza, had leaded to tremendous economic losses in the poultry industry. Furthermore, highly pathogenic avian influenza virus (e.g.. H5N1 subtype) could directly infect humans. In order to provide reference for the development and application of new animal feed additives, the co-effects of H5N1 subtype inactivated vaccine and GFP as feed additives of Beijing fatty chicken were investigated.

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