Volume 19 Part 1 Article 120: Evaluation of 5α-Reductase Inhibitory Activity of Certain Herbs Useful as Antiandrogens

Volume 19 Part 1 Article 120
Year 2016
Title: Evaluation of 5α-Reductase Inhibitory Activity of Certain Herbs Useful as Antiandrogens
Author: Alok Nahata

Abstract:
With a view to find out some potential 5α-Reductase (5αR) inhibitors from plant origin, we screened eleven herbs reported to have antiandrogenic properties for their 5αR inhibition potential. Ganoderma lucidum powder was obtained as a gift from Gano Excel Industries Pvt. Ltd, Malaysia. Urtica dioica roots were obtained from Nainital, India. CB, TT, PM, SI, CR, CC, BH, PN and EE were collected from the forest areas of Sagar India and were identified at the Department of Botany, Dr. Hari Singh Gour University, Sagar. All the herbs were coarsely powdered and extracted successively with petroleum ether, ethanol and water using Soxhlet apparatus to obtain the extracts.

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