Volume 19 Part 1 Article 118
Title: Lignosus rhinocerotis on Airway Muscle Relaxation
Author: Mei Kee Lee, Chon-Seng Tan, Szu Ting Ng, Kuan Hon Lim, Kang Nee Ting
Lignosus rhinocerotis (Tiger Milk Mushroom) has been used for 400 years by the communities in South East Asia for treating asthma and cough. It is from the family of Polyporaceae (Basidiomycota). The sclerotium is particularly of medicinal value1. Patients with asthma and chronic cough are known to have airway smooth muscle contraction and hence airway narrowing, leading to breathing difficulty. Asthmatic attack consists of early phase (airway contraction) and late phase (airway inflammation). Current mainstay of treatment of asthma is bronchodilators for early phase and corticosteroid for late phase2,3. No pharmacological studies published to date to support its most popular claims for treating cough and asthma. This study aims to investigate the direct relaxant effects of the L. rhinocerotis cold water extract on isolated rat airways.